KEY PUBLICATIONS

  • 2026, August 3rd

    Binda F, Buscemi L, Gurtner N, Hirt L, Chatton JY.

    HCAR1-mediated lactate signaling modulates motor behavior and regulates spontaneous firing in Purkinje cells

    iScience

    > Expand abstract

  • 2024, April 6th

    Alessandri M, Osorio-Forero A, Lüthi A, Chatton JY.

    The lactate receptor HCAR1: A key modulator of epileptic seizure activity

    iScience

    > Expand abstract

  • 2022, December 20th

    Nadia Rosenberg, Maria Reva, Francesca Binda, Leonardo Restivo, Pauline Depierre, Julien Puyal, Marc Briquet, Yann Bernardinelli, Anne-Bérengère Rocher, Henry Markram, Jean-Yves Chatton

    Overexpression of UCP4 in astrocytic mitochondria prevents multilevel dysfunctions in a mouse model of Alzheimer's disease

    Glia

    > Expand abstract

  • 2022, March 3rd

    Briquet M, Rocher AB, Alessandri M, Rosenberg N, de Castro Abrantes H, Wellbourne-Wood J, Schmuziger C, Ginet V, Puyal J, Pralong E, Daniel RT, Offermanns S, Chatton JY.

    Activation of lactate receptor HCAR1 down-modulates neuronal activity in rodent and human brain tissue

    J Cereb Blood Flow Metab

    > Expand abstract

  • 2019, June 5th

    de Castro Abrantes H, Briquet M, Schmuziger C, Restivo L, Puyal J, Rosenberg N, Rocher AB, Offermanns S, Chatton JY.

    The Lactate Receptor HCAR1 Modulates Neuronal Network Activity through the Activation of Gα and Gβγ Subunits.

    J Neurosci

    > Expand abstract