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2026, May 4th
Cosentino C, Klein R, Menoud V, Guay C, Aiello E, Auddino S, Di Giuseppe G, Ciccarelli G, Galli A, Alabiso F, Mangano E, Brozzi F, Bouzakri K, D'Adamo S, Cetrullo S, Quero G, Mari A, Alfieri S, Giaccari A, Mezza T, Dotta F, Sebastiani G, Regazzi R.
5'tRNA-derived fragments modulate β-cell homeostasis and islet macrophage activation in type 2 diabetes
Nat Commun
> Expand abstract
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2024, May 3rd
Jacovetti C, Donnelly C, Menoud V, Suleiman M, Cosentino C, Sobel J, Wu K, Bouzakri K, Marchetti P, Guay C, Kayser B, Regazzi R.
The mitochondrial tRNA-derived fragment, mt-tRF-LeuTAA, couples mitochondrial metabolism to insulin secretion
Mol Metab.
> Expand abstract
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2022, July 12th
Bayazit MB, Jacovetti C, Cosentino C, Sobel J, Wu K, Brozzi F, Rodriguez-Trejo A, Stoll L, Guay C, Regazzi R.
Small RNAs derived from tRNA fragmentation regulate the functional maturation of neonatal β cells
Cell reports
> Expand abstract
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2020, November 5th
Stoll L, Rodríguez-Trejo A, Guay C, Brozzi F, Bayazit MB, Gattesco S, Menoud V, Sobel J, Marques AC, Venø MT, Esguerra JLS, Barghouth M, Suleiman M, Marselli L, Kjems J, Eliasson L, Renström E, Bouzakri K, Pinget M, Marchetti P, Regazzi R
A circular RNA generated from an intron of the insulin gene controls insulin secretion
Nat Commun
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2019, February 5th
Guay C, Kruit JK, Rome S, Menoud V, Mulder NL, Jurdzinski A, Mancarella F, Sebastiani G, Donda A, Gonzalez BJ, Jandus C, Bouzakri K, Pinget M, Boitard C, Romero P, Dotta F, Regazzi R.
Lymphocyte-Derived Exosomal MicroRNAs Promote Pancreatic β Cell Death and May Contribute to Type 1 Diabetes Development.
Cell Metab.
> Expand abstract
